Short-Term Rental Regulations
in Ste. Genevieve County, MO

Airbnb listings are allowed in Ste. Genevieve County, MO, but with restrictions. No county-level STR ordinance exists; short-term lodging is governed by Missouri DHSS rules and Ste. Genevieve County Health Department inspections for sanitation and safety. Within the City of Ste. Genevieve, 'vacation rentals by owner' are classified as lodging establishments requiring annual registration, occupancy permits (with inspections upon change of occupancy), compliance with zoning/building codes, and smoke alarm safety standards. A permit is required before you can host. These rules apply to all short-term rental platforms (Airbnb, Vrbo, Booking.com, etc.) — not just Airbnb specifically. See the official source linked on this page for full requirements. Last verified 2026-05-14.

No county-level STR ordinance exists; short-term lodging is governed by Missouri DHSS rules and Ste. Genevieve County Health Department inspections for sanitation and safety. Within the City of Ste. Genevieve, 'vacation rentals by owner' are classified as lodging establishments requiring annual registration, occupancy permits (with inspections upon change of occupancy), compliance with zoning/building codes, and smoke alarm safety standards.

Yes, a permit is required to operate a short-term rental in Ste. Genevieve County. 1) For unincorporated county: Obtain a state lodging license by submitting an application to the Missouri DHSS/local public health agency, including an approved inspection report from the Ste. Genevieve County Health Department. 2) For City of Ste. Genevieve: Submit a city lodging/permit application to the Building Commissioner/City Clerk with a Missouri sales tax number, pass an occupancy inspection, and pay the required fees ($25 annual license fee for 5 or fewer rooms).

1) For unincorporated county: Obtain a state lodging license by submitting an application to the Missouri DHSS/local public health agency, including an approved inspection report from the Ste. Genevieve County Health Department. 2) For City of Ste. Genevieve: Submit a city lodging/permit application to the Building Commissioner/City Clerk with a Missouri sales tax number, pass an occupancy inspection, and pay the required fees ($25 annual license fee for 5 or fewer rooms).

Vrbo is permitted in Ste. Genevieve County, MO under the same restrictions that apply to Airbnb — local rules govern the rental itself, not the specific platform. You must hold a valid permit before hosting on Vrbo. Last verified 2026-05-14.

Short-term rental hosts in Ste. Genevieve County are typically responsible for lodging, occupancy, and applicable sales taxes — these usually apply even where hosting is allowed without a permit. Rates and remittance rules vary by jurisdiction (state, county, and city can each levy a share); confirm the current rates with the official source linked on this page. Platforms such as Airbnb and Vrbo collect some taxes automatically, but the host remains liable for any not collected on their behalf.

We are not currently tracking any recent short-term rental ordinance changes for Ste. Genevieve County. STR rules change frequently — verify the current requirements with the city or county before listing, using the official source linked on this page.